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2012;28:e2326

Gysin R, Kraftsik R, Boulat O, Bovet P, Conus P, Comte-Krieger E, et al

In another study, phosgene-exposed animals (500 ppm for 1 minute) received saline (positive control), a low (50 mg/kg), moderate (100 mg/kg), or high (200 mg/kg) dose of NAC, or were exposed to phosgene and untreated (control) (Ji et al., 2010)

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Several clinically relevant drug candidates, including TMZ, nitrosoureas, platinum agents, integrin inhibitors, EGFR inhibitors, VEGFR inhibitors, HDAC inhibitors, topoisomerase inhibitors, and doxorubicin, have been loaded into nanocarriers and tested in orthotopic animal models of GBM [164,216]