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doi: 10.1126/science.1222939

It was reported that receptors for the Fc fragment of IgG result in the removal of platelets coated with immunoglobulin ( Emerging data has demonstrated a strong association among platelet function, metabolites of gut microbiota, and lipid metabolism ( Methylbacillus , Sphingomonas , and Staphylococcus was negatively correlated with serum salicylate, which was previously found to induce ITP and inhibit platelet production in megakaryocytes ( Platelet metabolism and reactivity critically depend on lipid composition ( To date, the analysis of gut microbes and lipid metabolism in modulation of ITP-associated platelet function has not yet been reported

Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats

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