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doi: 10.1371/journal.pone.0204269 Anderson CP, Seeger RC, Satake N, Monforte-Munoz HL, Keshelava N, Bailey HH, Reynolds CP ( 2001 )

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

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Isatuximab was originally developed for its ability to operate via CDC, while Daratumumab was selected to enhance ADCC activity
