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PE-22-28 raises seizure threshold concerns via TREK-1 blockade Evidence integrity : Dihexa has a retracted key publication

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Zero-crossing after the p3-peak is the e-peak

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This is the foundational benefit from which many of the other effects are thought to follow

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it is not standard in UK clinical practice, where single-use Water for Injections BP is preferred

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PMC Brcic L, et al

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