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Biochim Biophys Acta (1960) 42:1878.10.1016/0006-3002(60)90779-4 97 LundP

In murine models, tobacco smoke exposure impairs immune responses to Haemophilus influenzae, a common pathogen responsible for acute COPD exacerbations

Prima A, Hara KY, Djohan AC, Kashiwagi N, Kahar P, Ishii J, et al

The GGAA core motif is critical for binding to copper-dependent gene sites (49)

However, the redox state is the principal mechanism through which ROS are integrated into cellular signal transduction pathways
