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Previously, we detected intracellular A aggregates (iA) in the pathways responsible for vesicular trafficking, including endocytosis and autophagy in old adult neurons from 3xTg-AD model mice [1]

In contrast, TCM presents a holistic alternative that addresses core PCOS pathologies including hyperandrogenism, insulin resistance, and inflammation, primarily via gut microbiota modulation

These effects highlight the importance of tight regulation of angiogenic factors and inhibitors

While these markers distinguish ferroptosis from apoptosis and necroptosis, certain stress conditions can activate some of these markers without activating ferroptosis (Figure 5)

Animal studies have demonstrated that probiotics can increase the production of SCFAs, leading to beneficial effects on gut health and liver function