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The therapeutic effects of pentadecapeptide BPC 157 occurred in reducing radiation-induced liver disease through Kruppel-like factor 4 upregulation both in vivo and in vitro [183]
Fast feedback occurs within seconds to minutes and involves inhibition of ACTH release by the corticosteroids, mediated through the glucocorticoid receptor (GR)

Arenas YM, Izquierdo-Altarejos P, MartinezGarca M, GimnezGarz C, Mincheva G, Doverskog M, et al

Kjrgaard K, Daugaard Mikkelsen AC, Landau AM, Eriksen PL, Hamilton-Dutoit S, Magnusson NE, Thomsen MB, Chen F, Vilstrup H, Mookerjee RP, et al

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