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Compared with controls, the experimental group showed a small, nonsignificant increase in leg muscle mass (+0.28 kg), but significant gains in appendicular muscle mass (+0.36 kg) and total lean mass (+0.92 kg)

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Mariano Malaguarnera, Lisa Cammalleri, Maria Pia Gargante, Marco Vacante, Valentina Colonna, Massimo Motta, l-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial2, The American Journal of Clinical Nutrition, Volume 86, Issue 6, 2007, Pages 1738-1744, ISSN 0002-9165, Colombani, Paolo & Wenk, Caspar & Kunz, Iris & Krahenbuhl, Stephan & Kuhnt, Martina & Arnold, Myrtha & Frey-Rindova, Petra & Frey, Walter & Langhans, Wolfgang