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Additionally, human atherosclerosis has been linked to mitochondrial oxidative stress (Petrucci et al., 2022) Mitochondrial ROS are utilized extensively as cellular messengers in signaling cascades
22 recently reported that Tyr164 of PGRMC1 is the axial ligand of haem because mutation of this residue impairs haem binding

A distance of 1-2 inches from the wound edge is typically recommended

doi:10.1038/newbio243085a0
