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First, curcumin can inhibit the inflammatory response by modulating the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) signaling pathway and reduce the expression of PD-L1, thereby relieving the immune suppression within the tumor microenvironment (Han et al., 2025)

Common measures of bio-oxidation include the measurement of protein carbonyls as an indicator of protein oxidation, assessment of isoprostanes, malondialdehyde, and 4-hydroxyl-2-nonenol as signs of lipid peroxidation, and evaluation of DNA oxidation by assaying the levels of the oxidized base, 8-hydroxy-2-deoxyguanosine (8-OH-dG) (98, 179, 209, 236)

The AKR1C3 encoded enzyme is also known as prostaglandin F synthase

It also helps in reducing wrinkles and fine lines and helps to give a young look to the skin

doi: 10.1186/1477-7827-11-48 18 HerwigRKnollCPlanyavskyMPourbiabanyAGreilbergerJBennettKL