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Moreover, the authors also noted significant improvements in behavior and dopaminergic functions in PD rats, suggesting that intranasal delivery of OE-MSCs may be a promising and minimally invasive alternative in PD treatment [104]

While systemic dihexa half life remains one to two hours, CNS concentrations may persist for four to six hours because the peptide is delivered to the target site without requiring blood-brain barrier penetration
[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Barchielli G., Capperucci A., Tanini D

The data indicates that C57BL/6NTac mice are more vulnerable to cpz toxin challenge in comparison to C57BL/6J mice

It is also involved in numerous metabolic processes, including detoxification and immune system support
