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HIF-1 regulates expression of numerous factors linked with angiogenic processes (particularly VEGF), glycolytic enzymes, and pro-metastatic genes
The large cells are more active in steroidogenesis and are influenced by various autocrine/paracrine factors such as inhibin, relaxin, and oxytocin (46, 47)

[DOI] [PubMed] [Google Scholar] 43.Zhong Q, Putt DA, Xu F, Lash LH

Hypothalamic Energy Homeostasis (ARCPVN Axis) Amylin receptor signaling in the arcuate nucleus (ARC) and paraventricular nucleus (PVN) of the hypothalamus modulates neuropeptide Y (NPY), AgRP, POMC, and CART expression, intersecting with leptin and GLP-1 receptor signaling networks
