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Description
doi: 10.1007/s11695-018-3187-y

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Clinical evaluation of large volume subcutaneous injection tissue effects, pain, and acceptability in healthy adults

And yes, this alone may be what causes your leaky gut and your subsequent Ulcerative colitis

At 0.5mm, a stamped microneedle traverses the stratum corneum (typically 10 to 30 microns), passes through the viable epidermis (50 to 100 microns), and lands in the upper papillary dermis (which begins around 100 to 150 microns deep)
