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doi: 10.1007/s11033-020-05875-9
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When considering the biological effects of IGF1 in second primary lung cancer, it has been shown that lung mesenchymal cells locally synthesize IGF1 which acts on the bronchial epithelium in a paracrine manner 56
Despite these advancements, therapies based on sotorasib and adagrasib face significant challenges due to the rapid development of acquired resistance
[DOI] [PubMed] [Google Scholar] 67.Batty M., Bennett M.R., Yu E
