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In addition, epigenetic studies have identified increased methylation in the promoter region of the glucocorticoid receptor (GR) gene, NR3C1, which may be related to altered receptor regulation and has also been associated with childhood trauma (Vangeel et al., 2015
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Future research should aim to stratify patients based on disease severity to determine whether bioactive compounds exert differential effects at various stages of periodontal destruction
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Once oxidized, the covalent bonds of DNA may be disrupted and thymine dimers may form, both of which make it unsuitable for use as evidence
