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Gonzalez-Bohorquez, D

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Unlike its parent protein, fragment 176-191 has been found to avoid certain effects, such as increasing insulin-like growth factor-1 (IGF-1) levels, affecting carbohydrate metabolism, reducing insulin sensitivity, and promoting long bone growth

122 discovered that AMPK-dependent autophagy is involved in the liver protection of IL-22 against APAP-induced liver injury

These molecules activate specific cell receptors (RAGE, LOX1, and TLR4), which trigger inflammatory responses and further contribute to cell damage