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Interestingly in pancreatic carcinomas the survival advantage of low GPx1 was associated with resistance to gemcitabine, a chemotherapeutic agent, in patients, and enhanced resistance to cell death in cell culture as well as increased xenograph tumor growth in mice

Research indicates that a high ratio of Firmicutes to Bacteroidetes in the gut microbiota of obese individuals may contribute to obesity, and this dysregulation is viewed as a potential cause of obesity in PCOS patients (75)

Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder

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