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Consequently, for statistical rigor and interpretive reliability, the quantitative meta-analysis was restricted to the subgroup of observational studies (k = 9), which allowed for robust effect size estimation and heterogeneity exploration

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If NNMT inhibition both restores adipocyte energy expenditure (promoting fat reduction) and supports myogenic differentiation (preserving or enhancing muscle), the net body composition effect could be recomposition simultaneous fat loss and lean mass preservation

doi:10.1111/anae.12948

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