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GEP , another key component of Gastrodia, is noted for its anti-inflammatory, anti-apoptotic, and immune-enhancing properties (Gan et al

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This synergy is thought to result from complementary intracellular signalling mechanisms GHRH receptor activation increases cAMP via Gs coupling, while ghrelin receptor activation increases intracellular calcium and activates protein kinase C via Gq/11 coupling

EMT is characteristic of the downregulation of E-cadherin and upregulation of N-cadherin and vimentin