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In the human adult brain, there are approximately 64,000 histaminergic neurons located in and around the TMN (Haas et al., 2008)

The Rosa26- Ai9 -tdTomato 21 reporter line contains a loxP -flanked stop cassette before the tdTomato cDNA
PubMed provides access to hundreds of research papers examining B12 absorption, deficiency risk factors, and supplementation strategies during weight loss

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Counter to broad-range inhibitors, CPPs can in theory target any surface-exposed stretch of amino acids to block specific protein-protein interactions and, in doing so, they can selectively modulate very specific downstream signaling events (Discussed in (de Keizer, 2017))