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Description
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
S., Kim, D
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T cells from SLE patients (227, 228) and lupus-prone mice (229) have abnormally high expression of CaMK4, which activates the AKT-mTOR pathway to promote Th17 cell development and IL-17 release.Th17 cell differentiation can be considerably decreased by blocking the CaMK4-AKT-mTOR pathway (230)
