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The presence of PGP at the peptides C-terminus might alter how it interacts with certain transporters or receptors on the blood-brain barrier
doi: 10.1038/nature14344 28 FengKLiuJGongLYeTChenZWangYet al
Imura, Y., Nishida, M., Ogawa, Y., Takakura, Y
The oxylipin signal jasmonic acid is activated by an enzyme that conjugates it to isoleucine in Arabidopsis
Preclinical research demonstrates that small molecules or stabilized peptide fragments may be absorbed through these tissues, though variability in saliva, pH, and mucosal permeability affects systemic exposure
