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These findings highlight the potential of plasma MOTS-c as a biomarker for monitoring insulin sensitivity, particularly in pre-diabetic lean individuals, where changes in MOTS-c levels could serve as an early indicator of insulin resistance

purpurata identified 6-gingerol, 8-gingerol, 10-gingerol, 4-shogaol, 6-shogaol, 10-shogaol, -pinene, 1,8-cineole, -pinene, and ( E )-methylcinnamate as major constituents (Shimoda et al., 2007)

Patients should be encouraged to adopt healthy eating habits and engage in regular physical activity to maximize the benefits of these treatments and reduce the risk of regaining weight once the treatments are discontinued