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Diabetes medications: May increase insulin or oral hypoglycemic requirements

Then, we'll review your medical history, looking at things like your diet (especially if you're vegan or vegetarian), your age, any stomach or gut conditions, past surgeries, and even the medicines you take, like metformin or proton pump inhibitors, which can sometimes affect B12 levels

Those with cardiovascular concerns should watch for any changes during treatment

How to Supplement with Methylated B12 Start low, go slow: Begin with 5001000mcg daily

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Last reviewed: May 13, 2026 Last updated: May 13, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations