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Thats because injected vitamin B12 enters the blood stream and stores in the livers muscle tissue

The Optimal Vitamin B12 Dosage for Kids, Pregnancy, and Seniors At age 50, everyone, regardless of diet should start supplementing with B12-fortified foods or supplements but over age 65 only high-dose daily supplements may suffice

Additionally, people who undergo gastric bypass (weight loss) surgery are prone to becoming B12 deficient

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However, for those with an underactive thyroid, absorption is often the problem