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McGill, R., Tukey, J

It is a cytoplasmic danger sensor that recognizes stress stimuli, such as ROS, ATP, and ionic flux, and induces the processing and secretion of pro-inflammatory cytokines, specifically IL-1 and IL-18, which promote inflammation and are responsible for renal tissue fibrosis [145]

Even so, no supplement replaces the basics sleep, diet and reducing direct pollution exposure still matter more than any capsule

GHKCu limits this by reducing pro-inflammatory cytokines (e.g., IL-6, TNF-) and promoting antioxidant defenses

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