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A study analyzing over 67,000 bacterial genomes identified 6738 genomes with putative CntA genes, predominantly in Proteobacteria, particularly Gammaproteobacteria (e.g., Escherichia and Acinetobacter )

Abbreviations ALC: Acetyl-l-carnitine DG: Dentate gyrus GFAP: Glial fibrillary acidic protein GSH: Reduced glutathione Kainate: Kainic acid MDA: Malondialdehyde MFS: Mossy fiber sprouting NF-kB: Nuclear factor-kappa B SE: Status epilepticus ROS: Reactive oxygen species SOD: Superoxide dismutase SE: Status epilepticus TLE: Temporal lobe epilepsy TNF-: Tumor necrosis factor- TBA: Thiobarbituric acid TLR4: Toll-like receptor 4 References Afshin-Majd S, Bashiri K, Kiasalari Z, Baluchnejadmojarad T, Sedaghat R, Roghani M (2017) Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinsons disease in the rat

Inflammatory cytokines like TNF-alpha and IL-6 interfere with insulin signaling and promote fat accumulation