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In summary, these potentially novel Mmut p.L690Ins/p.L690Ins mice recapitulate many of the biochemical and clinical presentations of MMA seen in human patients, survive into adulthood, and can be rescued with gene therapy

Case report]

Firstly, long-chain fatty acids are converted to long-chain acyl-CoA catalyzed by acyl-CoA synthetases in the endoplasmic reticulum and outer mitochondrial membrane

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