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doi: 10.1007/978-1-60761-938-3_5 5 SheproDMorelMLN

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An ATP-depleting futile 5-oxoproline cycle related to the glutathione synthetic pathway was recently proposed to explain many of the biochemical features of nephropathic cystinosis (38,39)

For example, research has largely focused on acute nitrate supplementation and its effect on endurance training performance

That can slow how the dose is used and is a known issue, particularly in women and larger patients where there is more tissue to pass through