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Based on previous data coming from preclinical and clinical studies and its excellent clinical safety profile, ALCAR is a promising treatment for ALS

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond

Collectively, these findings highlight L-carnitine as a mitochondria-targeted metabolic modulator with broad therapeutic implications

Microglia undergo metabolic reinvention: early succinate accumulation drives inflammatory rage, yet later oxidation of this metabolite switches them to anti-inflammatory phagocytes [37]

So, Weinberg et al hypothesized that overloading cells with exogenous fatty acids by infusing a lipid emulsion would exacerbate LA toxicity