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Physiol Rev 79(4):12831316 Franco M et al (2011) Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

Specifically, we used DCF, a drug often prescribed as a non-steroid anti-inflammatory drug, and OMZ, a proton pump inhibitor used for gastric acid inhibition 37 , both known to induce idiosyncratic DILI

This effect on heart rate is an important safety issue that needs special attention in future trials since obese individuals are at increased cardiovascular risk

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