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Description
A minimum sample size of 21 cases in each group is required to elicit this difference at an alpha level of 0.05 and a power of the study of 90%

Mechanism differences TRT directly supplies testosterone from external sources

Andreazza AC, Shao L, Wang JF, Young LT (2010) Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

(2) individuals with subclinical hypothyroidism, DIO2 polymorphisms, or borderline low fT3, who may require regular assessment of fT3, rT3, and relevant micronutrients

doi: 10.1111/neup.12607
