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Description
Loss of function mutations in PAPP-A2 (OMIM #619485) prevent this cleavage and reduce the amount of free circulating IGF-1
Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease
10.1093/neuonc/noab200 80 Ozyerli-GoknarE.Sur-ErdemI.SekerF.CingzA.KayabolenA.Kahya-YesilZ.et al (2019)
Nature 491 (7424), 473477
Metabolism N-Acetyl-SAC has been identified as a metabolite of SAC in urine of rats, dogs, and humans [20, 21]
