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2005 doi: 10.1056/NEJMra051884

Copper Ion (Cu)

These drugs independentlyand synergisticallyinduce severe B12 deficiencies by disrupting entirely different stages of the digestive process

BPC-157 has a half-life of roughly 4 to 6 hours, but the cellular repair processes it triggers continue well beyond that window

Despite the greater risk of nephrotoxicity associated with the drug, a retrospective study observed a lower recurrence rate when compared with intravenous methylprednisolone, in addition to the shorter therapeutic course.79,80 Other described treatments include intravenous immunoglobulin, mepolizumab, dupilumab and plasmapheresis, whit success described in a few case reports.27 Specific antiviral treatment (e.g., ganciclovir) is a controversial subject, and although not recommended by some authors,75 if signs and symptoms are suggestive and there is confirmation of viral reactivation, specific immunoglobulins and antivirals should be tried