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doi:10.1016/j.ijbiomac.2023.123558 Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T
doi: 10.4103/1673-5374.382254 [DOI] [PMC free article] [PubMed] [Google Scholar]
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Visible improvements usually appear within 812 weeks, with continued enhancement over several months
Timing: Why 30 to 60 Minutes Before Bed Matters DSIP's plasma half-life is 15 minutes, but the neuroendocrine cascade it triggers takes 20 to 40 minutes to fully engage
