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Hyperactive Notch signaling in GBM maintains stemness and confers therapy resistance by blocking differentiation [24,25,26,27,28]

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S4A) whereas most downregulated genes were enriched in muscle contraction, smooth muscle cell contraction and cation transport related GO terms for example Myh6 (log2FC = 6.85), Slc2a5 (log2FC = 6.04), Mstn (log2FC = 5.88), Mb (log2FC = 5.25), Myl1 (log2FC = 4.98), Myh6 (log2FC = 6.85), and Cacna1s (log2FC = 3.04) (Fig

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J Am Chem Soc 129:72197 NTP (2008) Toxicology and carcinogenesis studies of methylene blue trihydrate (Cas no
