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doi: 10.12659/MSM.933446 9 SapkotaHRNuneA

How do ROS induce netosis

ox-LDL is not recognized by the LDL receptor and is subsequently taken up by scavenger receptors in macrophages to form foam cells and so lead to atherosclerotic plaques (Boullier et al., and H 2 O 2 stimulate stress-related signaling mechanisms such as NF-B, p38-mitogen activated protein kinases (p38-MAPK) and signal transducers and activators of transcription-Janus kinases (STAT-JAK), resulting in vascular smooth muscle cell migration and proliferation

Genomics has found that patients with CFS have decreased mitochondrial DNA copy number (42) and ATP synthesis efficiency (73), suggesting increased genomic instability