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Description
Severe liver damage caused by therapeutic doses of acetaminophen
Kaplan AR, Glazer PM
Besides the purely structural role of some disulfide bonds, various effects can be ascribed to redox changes, as they can participate in catalytic, regulatory, protective and signaling mechanisms by promoting conformational changes and influencing proteinprotein interactions or subcellular localization which in fine affect the biological activity of the modified proteins
doi: 10.1038/nrc2069
Ngambenjawong C, Cieslewicz M, Schellinger JG, Pun SH
