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Science (2020) 368(6494):97380
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It is designed to address inflammation, tissue repair, collagen synthesis, and cellular remodelling through complementary biological mechanisms

According to Morgan and Curran (2012), withdrawal symptomssuch as anxiety, shaking, and sweating manifest, driving continued use to avoid these discomforts

[DOI] [PMC free article] [PubMed] [Google Scholar] 343.Yadava N, Nicholls DG

However, at high concentrations, when RNS levels exceed the capability of its detoxification in the biological system, serious damage to cells may occur [147, 148] due to inhibition of mitochondrial respiratory function by competing with O 2 for interaction with cytochrome oxidase [149] and via nitrative/nitrosative stress [150, 151]
