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177 During T cell activation, the TCR complex aggregates with signaling molecules in lipid rafts, such as the Src family lymphocyte-specific protein tyrosine kinase (Lck), thereby increasing signal transduction (Fig

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[PubMed] [Google Scholar] 8.McLean IW, Burnier MN, Zimmerman LE, Jakobiec FA

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IFN activates the JAKs/STAT pathway, increasing the expression of CXCR3 and its ligands CXCL9, CXCL10, and CXCL11, responsible for CD8 + T cell recruitment and apoptosis in melanocytes

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