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firmly established that the vicinal lipoate thiols in Odh can be rapidly oxidized by M amounts of H 2 O 2 followed by rapid S-glutathionylation of SOH groups in rat heart mitochondria (Nulton-Persson et al., 2003

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The same targeting mechanism allowed for selective delivery of ferroptosis inhibitors to the affected coronary territory, demonstrating superior cardioprotection compared to systemic therapy in experimental coronary occlusion models

The role of APOE4 in disrupting the homeostatic functions of astrocytes and microglia in aging and Alzheimer's disease