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In colonic tissue models, gabapentin was associated with: Reduced mast cell density or activation markers Decreased release of inflammatory mediators Improvement in visceral pain signaling These findings suggest gabapentin may exert indirect mast cellregulating effects within colonic tissue in experimental models

Neuroprotective effects of mitochondria-targeted Curcumin against rotenoneinduced oxidative damage in the cerebellum of mice

Additionally, transcriptomic analysis of small arteries from hypertensive patients with chronic kidney disease revealed that miR-338-3p targets GPX3

Roth S, Jung K, Jung H, Hommel RK, Kleber HP: Crotonobetaine reductase from Escherichia coli

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