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Dog breeds that benefit most from cobalamin supplements are Giant Schnauzers, Chinese Shar-Peis, Border Collies, Beagles, and Australian Shepherds, as they have a genetic predisposition to selective cobalamin malabsorption

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All procedures were approved by the University of Arizona Institutional Animal Care and Use Committee (IACUC)

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Inhibition of methylation of MBP has been shown to cause demyelination, further emphasizing the importance of this process in maintaining the structure and function of myelin [73], (Fig

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