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Description
Results To investigate a possible role of the phospholipid hydroperoxidase glutathione peroxidase 4 (GPX4) in protection from oxidative stress, we investigated GPX4 expression in postmortem human brain tissue from individuals with and without Parkinson's disease
Methods Human lipoaspirates were transplanted subcutaneously into the backs of normal saline-treated (control) or GSH-treated nude mice
Actives studied in wound-healing & longevity science
Therefore, screening for lead compounds able to activate this essential enzyme might protect neuronal cells from damage and slow the disease progression
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