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Moreover, BAs exert metabolic effects that indirectly influence HTN

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Foitzik et al

Importantly, anti-PCSK9 therapy will decrease circulating LDL cholesterol while increasing the exposure of PCSK9- and LDLR-expressing tissues to LDL cholesterol, perhaps providing a partial explanation for the contradictory anti- and pro- cancer effects of PCSK9 inhibition seen in different tumor models
