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And in the process, before our eyes, reinventing the art of acting." [223] As early as 1977, Newsweek remarked that the actor "gives you the shock of becoming, of a metamorphosis that can be thrilling, moving, or frightening." [224] Biographer Douglas Brode praises De Niro's versatility and ability to inhabit any role, although Pauline Kael once said in 1983 that she did not like how the actor was "disfiguring" himself in films such as Raging Bull

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The following skin bioengineering measurements [27] were assessed: (i) water content of the stratum corneum by Corneometer CM 825 (Courage-Khazaka, Cologne, Germany), (ii) transepidermal water loss (TEWL) by Tewameter TM 300 (Courage-Khazaka, Cologne, Germany), and (iii) sebum amount by Sebumeter SM 815 (Courage-Khazaka, Cologne, Germany) at baseline and weeks 4, 8, and 12