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doi: 10.3389/fped.2024.1496846 Received 15 September 2024 Accepted 25 November 2024 Published 23 December 2024 Volume 12 - 2024 Edited by Raul Chavez-Valdez, Johns Hopkins Medicine, United States Reviewed by Johana Diaz, University of Maryland, United States Jennifer Fundora, Johns Hopkins University, United States Updates Copyright 2024 Chamakioti, Brion, Viswanathan, Lair and Angelis

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This form of targeted delivery reduces systemic exposure to doxorubicin and, in doing so, it significantly mitigates cardiotoxicity as well as general toxicities associated with conventionally administered doxorubicin