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Disulfide-containing linkers are primarily linked to maytansinoid payload classes, and the reactivity of disulfide bonds can be regulated by steric hindrance: alpha methyl substitution significantly affects reduction rate and resistance to thiol-disulfide exchange force

Emerging efforts to evaluate the role of the susceptibility loci for pulmonary fibrosis have led to unexpected results, as demonstrated by the discovery of the association of MUC5B variant with disease risk, but improved disease prognosis

This combination addresses the metabolic depletion hangover causes even if glutathione absorption is suboptimal

By supporting liver function, it aids in the elimination of toxins that can manifest as skin issues

doi: 10.1073/pnas.1512243112 68 LinXHLassGKongLSWangHLiXFHuangHFet al