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Most of that research used oral supplements, not injections

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Direct provision of TMAO into diet has been shown to increase the development of atherosclerosis in animal models, confirming its pro-atherogenic properties 47 , and multiple clinical studies have confirmed that an elevated TMAO level is associated with increased risks for incident major adverse CV events 48
Pinetown Watkins, Ann B

Quantifying triglyceride-rich lipoprotein atherogenicity, associations with inflammation, and implications for risk assessment using non-HDL cholesterol
