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There, p53 forms a complex with mitochondrial transcription factor A (TFAM) and mtDNA to initiate transcriptional programs that drive mitochondrial biogenesis and antioxidant defenses, key adaptations underlying the benefits gained during physical exercise training [203, 254]

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ginseng, Rehmannia glutinosa, Acorus tatarinowii, Yuan Zhi, Epimedium brevicornu ) demonstrates sustained cognitive improvements over 24 months (Shi et al

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